Streptococcus spp.
| Morphology | Gram-positive coccus or spherical, non-sporeforming facultative anaerobic bacteria that grows in pairs or chains. | 
|---|---|
| Disease | Pharyngitis, pneumonia, meningitis, endocarditis, necrotizing fasciitis, urinary tract infections. | 
| Zoonosis | Yes | 
| Host Range | Humans and animals (cattle, poultry, fish, reptiles). | 
|---|---|
| Modes of Transmission | Ingestion, exposure of mucous membranes, penetration through skin; wound contamination. | 
| Signs and Symptoms | Respiratory and gastrointestinal illness, diarrhea, redness and swelling at site of infection. | 
| Infectious Dose | >10^6-10^7 organisms. | 
| Incubation Period | Days to weeks | 
| Prophylaxis | None. | 
|---|---|
| Vaccines | None. | 
| Treatment |  | 
| Surveillance | Monitor for symptoms of infection. | 
| MSU Requirements | Report any exposures | 
| Laboratory Acquired Infections (LAIs) | Cases have been reported | 
|---|---|
| Sources | Cultures, frozen stocks, other samples described in IBC protocol. | 
| Canadian MSDS: | |
|---|---|
| BMBL | |
| CDC |  | 
| NIH Guidelines | 
| Risk Group 2 | Agents that are associated with human disease which is rarely serious and for which preventive or therapeutic interventions are often available. | 
|---|---|
| BSL2 | For all procedures involving suspected or known infectious specimen or cultures. | 
| ABSL2 | For all procedures utilizing infected animals. | 
| Small | Notify others working in the lab. Remove PPE and don new PPE. Cover area of the spill
                                                                  with absorbent material and add fresh 1:10 bleach:water. Allow 20 munutes (or as directed)
                                                                  of contact time. After 20 minutes, cleanup and dispose of materials. | 
|---|---|
| Large | 
 | 
| Mucous membrane  | Flush eyes, mouth, or nose for 5 minutes at eyewash station. | 
|---|---|
| Other Exposures  | Wash area with soap and water for 5 minutes.  | 
| Reporting | Immediately report incident to supervisor, complete a First Report of Injury form, and submit to Safety and Risk Management. | 
| Medical Follow-up  | During business hours: Bridger Occupational Health 3406 Laramie Drive. Weekdays 8am -6pm.  Weekends 9am-5pm After business hours: Bozeman Deaconess Hospital Emergency Room 915 Highland Blvd Bozeman, MT | 
| Disinfection | 1:10 bleach:water; or 70% ethanol. | 
|---|---|
| Inactivation | Inactivated by moist heat (15 min at 121°C) and dry heat (1 hour at 170°C) | 
| Survival Outside Host | Survives in mud, litter, and sediment, limited survival on surfaces. | 
| Minimum PPE Requirements | Lab coat, disposable gloves, safety glasses, closed toed shoes, long pants | 
|---|---|
| Additional Precautions | Additioanl PPE may be required depending on lab specific SOPs and IBC Protocol. | 
